ndi China (S) -1-Boc-3-hydroxypiperidine Kupanga ndi Fakitale |Hengkang
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(S) -1-Boc-3-hydroxypiperidine

Kufotokozera Kwachidule:

chithunzi4

CAS: 143900-44-1

Chithunzi cha C10H19NO3

MW: 201.26


Tsatanetsatane wa Zamalonda

Zogulitsa Tags

Magulu azinthu

ChiralReagents;Piperidines;Heterocycles;Intermediates & Fine Chemicals;mankhwala; Anticancer

Mawu ofanana ndi mawu

(S) -1-Boc-3-Hydroxypiperidine

(S) -1-N-BOC-3-HYDROXY-PIPERIDINE

(S) -3-HYDROXY-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

(S) -3-HYDROXY-1-(TERT-BUTOXYCARBONYL)PIPERIDINE

(S) -1-BOC-3-PIPERIDINOL

(S)-N-(TERT-BUTOXYCARBONYL)-3-HYDROXYPIPERIDINE HYDROCHLORIDE

(S) -N-BOC-3-HYDROXY PIPERIDINE

(S)-TERT BUTYL-3-HYDROXYPIPERIDINE-1-CARBOXYLATE

(S) -1-(tert-Butoxycarbonyl) -3-hydroxypiperidine

S-1-Boc-3-hydroxypiperidine

(3S) -hydroxy-1-piperidinecarboxylic acid 1,1-dimethylethyl ester

(S) -3,5-DifluoroMandelic asidi

(S) -tert-Butyl 3-hydroxypiperidine-1-carboxylate

(S) -tert-Butyl-3-hydroxypiperidine-1-carboxylate tert-butyl

(3S) -3-hydroxy piperidine-1-carboxylate tert-butyl

(S) -3-hydroxypiperidine-1-carboxylate

(3S) -3-Hydroxypiperidine, N-BOC yotetezedwa

(S) -N-tert-Butoxycarbonyl-3-hydroxypiperidine

Chemical Properties

Malo osungunuka: 34-40 ° C

Malo otentha: 292.3±33.0 °C (Zonenedweratu)

Kachulukidwe: 1.107±0.06 g/cm3(Zonenedweratu)

Fp: 110 °C

Kutentha kosungira: Khalani pamalo amdima, Osindikizidwa owuma, Kutentha kwachipinda

Kusungunuka: Kusungunuka mu methanol.

Pka: 14.74±0.20 (Zonenedweratu)

Fomu: Ufa kapena Crystalline Ufa

Mtundu: Woyera mpaka tani

ntchito ya kuwala: [α]22/D +10.0°, c = 1 mu chloroform

InChIKey: UIJXHKXIOCDSEB-QMMMGPOBSA-N

Chidziwitso changozi

1 Gulu la chinthu kapena kusakaniza

Kukwiya pakhungu, Gawo 2

Kupweteka m'maso, Gawo 2

Chiwopsezo cha chiwalo chandandandandandawu - kuwonekera kamodzi, Gulu 3

2 GHS label zinthu, kuphatikiza mawu osamala

Zithunzi  chithunzi5
Chizindikiro cha mawu Chenjezo
Ndemanga zangozi H315 Imayambitsa kuyabwa pakhungu

H319 Imayambitsa kuyabwa kwamaso kwambiri

H335 ikhoza kuyambitsa kupsa mtima

Ndemanga zotetezedwa
Kupewa P264 Sambani ... bwinobwino mutagwira.

P280 Valani magolovesi oteteza / zovala zoteteza / zoteteza maso / zoteteza kumaso / zoteteza kumva / ...

P261 Pewani kupuma fumbi/fume/gesi/mist/vapours/spray.

P271 Gwiritsirani ntchito panja kapena pamalo olowera mpweya wabwino.

Yankho P302+P352 NGATI PAKHUMBA: Sambani ndi madzi ambiri/...

P321 Chithandizo chapadera (onani ... pa chizindikiro ichi).

P332+P317 Ngati kuyabwa pakhungu kumachitika: Pezani chithandizo chamankhwala.

P362+P364 Chotsani zovala zomwe zili ndi kachilombo ndikuzichapa musanagwiritsenso ntchito.

P305+P351+P338 NGATI M'MASO: Sambani mosamala ndi madzi kwa mphindi zingapo.Chotsani magalasi olumikizirana, ngati alipo komanso osavuta kuchita.Pitirizani kutsuka.

P304+P340 NGATI WOPHUNZITSIDWA: Chotsani munthu kumpweya watsopano ndikukhala womasuka kupuma.

P319 Pezani thandizo lachipatala ngati simukumva bwino.

Kusungirako P403+P233 Sungani pamalo abwino mpweya wabwino.Sungani chidebe chotsekedwa mwamphamvu.

P405 Store yatsekedwa.

Kutaya P501 Tayani zamkati/zotengera kumalo oyenera kuchiza ndi kutaya zinthu molingana ndi malamulo ndi malamulo omwe akugwiritsidwa ntchito, komanso mawonekedwe azinthu panthawi yotaya.

3 Zowopsa zina zomwe sizimayika m'magulu

palibe deta yomwe ilipo

Mafotokozedwe a Zamalonda

Maonekedwe/mtundu Yoyera mpaka yoyera yolimba
Itha kukhala agglomerate pambuyo posungira nthawi yayitali
Identity (IR) Amafanana
Kuyesa (HPLC w/w) 97.0% -103.0%
Chemical purity (GC area) ﹦ 99.0%
Chiyero chonyansa (GC w/w) 3-Hydroxypiperidine﹦ 0.1%
3-Hydroxypyridine﹦ 0.20% Sanapezeke
1-Boc-3-piperidone﹦ 0.10% Sanapezeke
1-Boc-4-hydroxypiperidine﹦ 0.10% Sanapezeke
Mtengo wa 1.96RRT﹦ 0.2% Sanapezeke
Chidetso chilichonse chosadziwika bwino﹦ 0.08% 0.01%
Chiral purity (HPLC area) ﹦ 99.5%
Methanol (GC) ﹦ 50ppm
Ethanol (GC) ﹦ 50ppm
DCM (GC) ﹦ 500ppm
Madzi (KF vol w/w) ﹦ 0.5%

Ubwino wathu

1: Fakitale yathu idazindikira kupanga kwakukulu kwamalonda kuyambira chaka cha 2012, kugulitsa kwapachaka kwafika kupitilira 20tons.
2 Wakhala wothandizira woyenerera ku kampani ya mankhwala a patent ya Ibrutinib.
3 Ubwino wazogulitsa ndi wapamwamba: Kuyesa: 97.0% -103.0%
Kuyera kwa Chemical (GC): ﹦ 99.0%
Chidetso chilichonse chosadziwika bwino﹤ ﹦ 0.08%
Chiral purity(HPLC area): ﹥ ﹦ 99.5%
4 Zimapangidwa ndi njira ya Chemical Resolution.
5 Njira zonse zoyesera ndizovomerezeka.
6 Msonkhano umodzi wodzipereka wopangira.


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